I never realised how much I rely on Tweetdeck until today when all my columns became corrupted and I could no longer receive tweets through it. I tried the usual delete the app etc, but this did not work, every time I re-installed, when it loaded it had the same problems! This was so frustrating. I even tried removing Adobe AIR with no success! In the end I managed to resolve the issue, by following the steps listed below. Delete TweetDeck.app from your application folder Delete any file or folder named TweetDeck under “home/Library/Preferences/TweetDeck” Re-install TweetDeck Quite easy really, but took me a while to find the TweetDeck preferences files. Please bear in mind that removing these files will delete any of your searches or saved columns. Not a big deal for me, but I know other people have hundreds….